milk thistle

Date: 2006-03-14 06:51 am (UTC)
Here's a traditional remedy for toxic hepatitis. Again, I don't want to steer you wrong, jeneralist has an herbal desk reference. Maybe give her a call.


Francine Rainone. American Family Physician. Kansas City: Oct 1, 2005.Vol.72, Iss. 7; pg. 1285, 4 pgs

Headnote]
Milk thistle has been used as a cytoprotectant for the treatment of liver disease, for the treatment and prevention of cancer, and as a supportive treatment of Amanita phalloides poisoning. Clinical studies are largely heterogeneous and contradictory. Aside from mild gastrointestinal distress and allergic reactions, side effects are rare, and serious toxicity rarely has been reported. In an oral form standardized to contain 70 to 80 percent silymarin, milk thistle appears to be safe for up to 41 months of use. Significant drug reactions have not been reported. Clinical studies in oncology and infectious disease that are under way will help determine the efficacy and effectiveness of milk thistle. (Am Fam Physician 2005;72:1285-8. Copyright © 2005 American Academy of Family Physicians.)


Milk thistle (Silybum marianum) was used in classical Greece to treat liver and gallbladder diseases and to protect the liver against toxins. It recently has been investigated for use as a cytoprotectant, an anticarcinogen, and a supportive treatment for liver damage from Amanita phalloides poisoning. Its active ingredient is silymarin, found primarily in the seeds. Silymarin undergoes enterohepatic recirculation, which results in higher concentrations in liver cells than in serum.1 It is made up of components called flavonolignans, the most common being silybin.2

This article was a literature review. It has recommendations for physicians but this is a pdf picture that I cannot attach. I will try to stick it in the Yahoo group files as with other things I can find.
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